Descriptions of Soranib 200 mg
Soranib 200 mg is used to treat late-stage kidney cancer (advanced renal cell carcinoma), liver cancer (hepatocellular carcinoma) that cannot be treated by surgery, and differentiated thyroid cancer that has come back or spread to other parts of your body. Sorafenib is an antineoplastic (cancer) agent. It interferes with the growth of cancer cells, which are eventually destroyed by the body.
This medicine is available only with your doctor’s prescription.
Proper Use of Soranib 200 mg
Soranib 200 mg used to treat cancer are very strong and can have many side effects. Before using this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.
This Soranib 200 mg comes with a patient information leaflet. Read and follow these instructions carefully. Ask your doctor if you have any questions.
Swallow the Soranib 200 mg whole with water. Do not crush, break, or chew it.
Take the tablet on an empty stomach, at least 1 hour before or 2 hours after a meal.
How Soranib 200 mg tablet works
Soranib 200 mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
This Soranib 200 mg works as a kinase inhibitor by inhibiting the enzyme RAF kinase that is an essential part of the RAF/MEK/ERK signalling pathway responsible for the growth and proliferation of cancerous cells. It also blocks certain cell surface kinases essential for angiogenesis, such as VEGFR-2, VEGFR-3, and PDGFR.
The dose of this Soranib 200 mg will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of Soranib 200 mg that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For oral dosage form (tablets):
- For kidney, liver, or thyroid cancer:
- Adults—400 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed and tolerated.
- Children—Use and dose must be determined by your doctor.
- For kidney, liver, or thyroid cancer:
If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage of Soranib 200 mg
Store the Soranib 200 mg in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects.
Using this medicine while you are pregnant can harm your unborn baby. It may also cause birth defects if the father is using it when his sexual partner becomes pregnant. Female patients should use effective birth control during treatment with this medicine and for at least 6 months after the last dose. Male patients who have female partners should use effective birth control during treatment with this medicine and for at least 3 months after the last dose. If you think you have become pregnant while using this medicine, tell your doctor right away.
Your blood pressure should be checked weekly, especially during the first 6 weeks after starting this medicine. Your doctor may need to treat you if you develop high blood pressure while you are using this medicine. Symptoms of high blood pressure include: blurred vision, dizziness, nervousness, headache, pounding in the ears, or a slow or fast heartbeat.
1.How is Soranib Tablet administered?
Soranib Tablet is an oral medicine and you should take it exactly as per your doctor’s advice. It can be taken without food or with low to moderate fat meal. It should not be taken with high-fat meal which will make Soranib Tablet less effective. If you are taking high-fat meal, take Sorafenib 1 hour before or two hours after high-fat meal.
2.For how long do I need to take Soranib Tablet?
If Soranib Tablet suits you well, then you should continue taking it for the duration suggested by the doctor. However, if you experience any side effect that bothers you, talk to your doctor immediately.
3.Do I need to take a treatment along with Soranib Tablet for it to work?
Soranib Tablet is used as a monotherapy, that is, it is a medicine which is used alone rather than in combination with other treatments like radiotherapy or chemotherapy.
4.How do I know if I am responding to Soranib Tablet?
While receiving treatment with Soranib Tablet, your doctor will most likely recommend regular scans to monitor the size of the tumor. You may also need to get regular blood tests to see if the deranged liver or kidney functions have improved or not.
5.What are the serious side effects that can occur while taking Soranib Tablet?
The possible serious side effects that may occur (not in everyone) include heart attack and heart failure, increased risk of bleeding, high blood pressure, skin problems and wound healing problems. Some other side effects which get highlighted when you go through various tests are decreased blood flow to the heart, swelling of the liver, an opening in the wall of stomach or intestines (perforation), changes in electrical activity of the heart (QT prolongation) and changes in thyroid hormone levels.
6.Does Soranib Tablet affect blood sugar levels?
Yes, Soranib Tablet can cause a decrease in the blood sugar levels. In fact, the levels can decrease to the extent that the patient may faint. So, it is important that the patients having diabetes check their blood sugar levels regularly. Additionally, you should also consult the doctor if the dose of anti-diabetic medicines needs to be adjusted.
7.I have developed redness and pain in my palms and soles ever since I started using Soranib Tablet. My skin is also coming off. Is this dangerous? What should I do?
It seems you have developed hand and foot skin reaction due to Soranib Tablet. Consult your doctor who will either interrupt your therapy for sometime or change your dose. He might also suggest some cream or lotion to treat the problem. If the problem is severe, consult a skin doctor.