Description
Erectile dysfunction (ED), also known as impotence, in men is treated with the Avanafil 100 mg Tablet. Physical factors such as an injury or illness, as well as psychological ones such as anxiety, stress, and depression, can induce reduced blood flow.
This drug relaxes the smooth muscles in blood vessel walls, allowing more blood to flow to the penis. Depending on the severity of the problem, Avanafil 100 mg Tablet may or may not work if the underlying cause of erectile dysfunction is psychological.
Avanafil 100 mg is another phosphodiesterase 5 inhibitor. It will compete with sildenafil, tadalafil and vardenafil as a treatment for erectile dysfunction. By inhibiting phosphodiesterase 5, these drugs stop the breakdown of cyclic guanosine monophosphate. This molecule is responsible for the smooth muscle relaxation in the corpus cavernosum which enables the inflow of blood that results in erection.
The tablets are rapidly absorbed. Maximum plasma concentrations are reached in 30–45 minutes and in some men, erection occurs 20 minutes after a 100 mg dose of Avanafil 100 mg. Absorption is delayed by food. So the tablets may take longer to work if taken after a meal.
Avanafil also has pharmacodynamic interactions. Nitrates, such as glyceryl trinitrate, increase concentrations of guanosine monophosphate, so their action can be potentiated by phosphodiesterase inhibitors. This can cause severe hypotension. Avanafil 100 mg is therefore contraindicated in patients taking nitrates. Its vasodilatory action may also have an additive effect with alcohol and antihypertensive drugs, particularly alpha blockers.
A total of 712 patients who had completed two of the efficacy studies of avanafil continued in a 52–week open-label extension study. Most of the patients asked to use Avanafil 100 mg. The average treatment duration was 35 weeks with only 153 men using the drug for 52 weeks. They were required to attempt sex at least four times a month. Approximately 80% were able to penetrate their partners and for 65% intercourse was successful.
In the meta-analysis the main adverse effects of Avanafil 100 mg were headache, flushing and nasal congestion. Compared to placebo, there was not a significant difference in the number of patients stopping treatment because of adverse effects.
There are some adverse effects which have occurred with other phosphodiesterase inhibitors that are an indication for stopping Avanafil 100 mg. These include loss of vision or hearing. In the open-label extension study one patient developed cyanopsia. All phosphodiesterase inhibitors can cause priapism.
Physical causes of erectile dysfunction include cardiovascular disease, but these patients may not be suitable for treatment with avanafil. It is contraindicated in men with hypertension, unstable angina and congestive heart failure.
Not all patients will respond to Avanafil 100 mg and in those that do the erection may not last long enough for successful intercourse. It is therefore similar to other phosphodiesterase 5 inhibitors. Although the patients in the extension study favoured the 200 mg dose to the 100 mg dose, the difference in efficacy may be limited.
A meta-analysis of 82 trials involving over 47,000 patients helps to suggest the place of avanafil in therapy. Although the confidence intervals overlap, Avanafil 100 mg appears to have lower efficacy relative to sildenafil. However, avanafil has a lower frequency of adverse effects, depending on the dose. Avanafil 100 mg had an adverse event rate similar to that of sildenafil 100 mg, but its efficacy was less.
How Avanafil 100 works
Avanafil 100 mg blocks phosphodiesterase enzyme in the body and releases chemical called nitric oxide, which helps to relax the smooth muscles and blood vessels supplying the inner part of penis. This increases the supply of blood flow to the penis which helps to obtain and maintain an erect penis when an individual is sexually excited. This medicine works only if you are sexually stimulated. Â Â
About Avanafil 100 mg
Money is important, but without fulfilment, nothing is complete. You should be happy with the task you’ve completed, the meal you’ve prepared, the game you’ve played, or the song you’ve chosen. Similarly, you and your lover both claim to be satisfied after sexual interactions. Depression takes over when a treatment is no longer enjoyable but rather frustrating due to a variety of circumstances.
In such situations, you will demand assistance in order to reach the highest level of sexual satisfaction. Avanafil 100 mg is a supplement that helps men rediscovers their manliness and sense of fulfilment.
How Avanafil 100 mg works?
The drug aids in the erection of the penis, but it does not cause it. A significant volume of blood must reach the penis during sexual stimulation to keep it erect. Avanafil 100 mg online helps to achieve this by lowering blood pressure, relaxing pelvic muscles, and smoothing erectile tissues.
Blood gushes in the penis blood vessels as soon as the patient is stimulated. The penis gets firm and erect as a result, which can help with orgasm. For the correct dosage, consult your doctor.
In a 24-hour period, do not take more than one dose of the medicine. The drug will not cause erections if there is no sexual trigger; thus, taking the pill alone will not produce erections. If your erection lasts longer than four hours, you should consult your doctor as soon as possible.
Read the Patient Information Leaflet if available from your pharmacist before you start taking Avanafil 100 mg and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with or without food as directed by your doctor, usually as needed. This medication is available in different doses. Depending on your dose, take avanafil about 15 minutes or 30 minutes before sexual activity. Follow your doctor’s instructions carefully on how many minutes before sexual activity you should take this medication. Do not take more than once daily.
The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Expert advice for Avanafil 100 mg
- Take Avanafil exactly as your doctor tells you to. It is intended to be taken before sexual activity and is not to be used daily.
- Avoid alcohol since it can reduce your ability to get an erection and may prevent you from getting the maximum benefits of this medicine.
- Let your doctor know if you have any heart disease, high or low blood pressure, or a history of heart attack.
- If you experience sudden visual disturbances, stop taking Avanafil and consult your doctor immediately.
Use of Avanafil 100 mg
Avanafil 100 mg is used to treat erectile dysfunction, or ED. Avanafil 100 mg triggers changes in the body that lead the penis to become erect in this scenario.
The second use of the medication is to treat pulmonary arterial hypertension (PAH). It works by reducing blood pressure in the arteries that transport blood to the organs.
How to take Avanafil 100mg?
Avanafil 100mg effects can last for up to 4-5 hours after you consume them. Take only one tablet every day if you intend to have sex. Your Avana dose should be as directed by your doctor, and it may be changed if it is too strong or too weak.
Missed a dose of Avanafil 100 mg
Don’t take any other medicines that day, and skip the drug’s dosage. The second dose should be taken the next day, according to the doctor’s instructions.
Some people take additional medicines the next day to make up for the missing day. Because such scenarios can lead to a drug overdose, such decisions should be avoided.
Side effects
- Muscle pain
- Sore throat
- Headache
- Arm, back or jaw pain
- Chest pain and discomfort
- Bladder pain
- Sweating
- Dizziness
- Fast or slow heartbeat
Precaution
If you have a circulation or heart problem that makes sexual intercourse unsafe, or if you’ve had a heart attack or stroke in the past six months
Have a vision-threatening eye condition like non-arteritic anterior ischemic optic neuropathy (NAION), or if you have retinitis pigmentosa, have factors that lead to priapism (erections lasting 4 hours or more) including penile anatomical deformity, sickle cell anaemia, multiple myeloma, or leukaemia.
directions for use
Take avanafil 100 exactly as advised by your doctor. Swallow the medicine with a glass of water. It is advised to take avanafil 100 15 minutes before intercourse to get better results. Your doctor will decide the correct dose and duration for you depending upon your age and severity of the condition. Â
FAQs:
1.How long does Avanafil stay in your system?
Sildenafil takes about 30 minutes to activate and lasts for four hours. avanafil price can start acting in as little as 15 minutes, and the benefits can last up to 6 hours.
2.Is Avanafil 100 mg ever going to be available over-the-counter?
Avanafil 100 mg online is not available at regular pharmacies or health stores. It can only be obtained with a valid prescription from a doctor or other medical professional.
3. What Avanafil 100 mg dosage should I take?
Your doctor will tell you how much to take and when to take it. 15 minutes prior to s*xual activity, take Avanafil dosage. Your doctor or healthcare provider may change your dose if necessary.
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