Xovoltib 50 mg (Afatinib Dimaleate)

Xovoltib 50 mg

Xovoltib 50 mg Tablet is a drug that is used to treat a particular type of lung cancer which is known as non-small cell lung cancer. It spreads to other parts of the body too. This belongs to a class of drugs known as kinase inhibitors.

It is the dimaleate salt form of afatinib. An orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic activity. This drug works by slowing or stopping the growth of cancer cells. It binds to a certain protein (epidermal growth factor receptor-EGFR) in some tumors.

 Before using this drug, inform your doctor about your current list of medications, over the counter products, allergies, pre-existing diseases, and current health conditions. Some health conditions may make you more susceptible to the side-effects of the drug.

Take as directed by your doctor. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.

• Avoid prolonged sun exposure
• Do not take 2 doses at once
• Planning to get pregnant
• Take this medicine on an empty stomach

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

What are the uses of Xovoltib 50 mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xovoltib 50 mg Tablet is to be taken empty stomach.

Following conditions can be restored by utilising this prescription

• Small Cell Lung Cancer
• Cancer

How does Xovoltib 50 mg work?

This medication behaves as a kinase inhibitor which irreversibly binds the kinase domains of EGFR (ErbB1), HER2 (ErbB2), and HER4 (ErbB4) to inhibit autophosphorylation of tyrosine kinase. This causes ErbB signalling downregulation and tumour growth inhibition.

Xovoltib 50 mg Tablet is an anti-cancer medication. It works by binding and inhibiting the enzyme receptors (EGFR, HER2, and HER4) that are responsible for the growth of cancer cells. Hence, resulting in the downregulation of signaling pathways. This is how it to stop or slow the spread of cancer.

• Are there any missed dose instructions?

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

• Are there any overdose instructions?

Seek emergency medical treatment or contact the doctor in case of an overdose.

What are the interactions of Xovoltib 50 mg Tablet ?

Whenever you take more than one medicine, or mix it with certain foods or beverages, you”re at risk of a drug interaction.

• Interaction with Alcohol

No information available.

• Interaction with Lab Test

No information available.

• Interaction with Medicine

This medication interacts with rifampicin, carbamazepine, phenytoin, phenobarbital, ritonavir, cyclosporine A, ketoconazole, itraconazole, erythromycin, verapamil, quinidine, tacrolimus, nelfinavir, saquinavir, and amiodarone.

• Interaction with Food

No information available.

• Interaction with Disease

FAQs about Xovoltib 50 mg Tablet

1.What is Xovoltib 50mg Tablet?

Ans: This drug is helps in treating a certain type of lung cancer(non-small cell lung cancer) that has spread to other parts of the body. It belongs to a class of drugs known as kinase inhibitors.

2.How long do I need to use Xovoltib 50mg Tablet before I see improvement in my condition?

Ans: This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor. Also taking this medication longer than it was prescribed, can cause an inadequate effect on the patient’s condition.

3.At what frequency do I need to use Xovoltib 50mg Tablet?

Ans: The duration of effect for this medicine is dependent on the severity of the patient’s condition. Therefore the frequency of usage of this medication will vary from person to person. It is advised to follow the proper prescription of the doctor, directed according to the patient’s condition.

4.Should I use Xovoltib 50mg Tablet empty stomach, before food or after food?

Ans: This medication is advised to be consumed orally. The salts involved in this medication react properly if it is taken after having food. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

5.What are the instructions for the storage and disposal of Xovoltib 50mg Tablet?

Ans: This medication contains salts which are suitable to store only at room temperature, as keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children.

OTHERS

Before taking Xovoltib 50 mg TABLET, inform your doctor if you:

• Are female and have low body weight less than 50 kg
• Have eye problems such as severe dry eyes, or ulcers involving the outer part of the eye (sclera) or use contact lenses
• Are informed of intolerant to some sugars such as lactose

Use in Pediatrics:

Xovoltib 50 mg TABLET is generally not recommended for use in children and adolescents (below 18 years). Consult your doctor before taking Xovoltib 50 mg TABLET.

Use in Geriatrics:

Xovoltib 50 mg TABLET should be used with caution in elderly patients (aged 65 years or above). Consult your doctor before taking Xovoltib 50 mg TABLET.