Cycloxan (Cyclophosphamide)

PRODUCT INTRODUCTION

Cycloxan 50mg Tablet is used in the treatment of different kinds of cancers. It is also used to treat kidney disease known as nephrotic syndrome in children after other treatments have not worked. It may be also used to treat other conditions, as determined by the doctor.

Cycloxan 50mg Tablet should be taken with food preferably in morning but at the same time every day to get the most benefit. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this cycloxan substitute medicine include vomiting, nausea, hair loss, fever, and blood in urine. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of cycloxan tablet

Malignant cancers

This medicine is used for the treatment of different types of malignant cancers such as multiple myeloma (cancer that affects plasma cells), certain types of leukemia (blood cancer), including chronic lymphocytic leukemia, acute myeloid leukemia, acute lymphoblastic leukemia, and acute myelogenous leukemia, Hodgkin’s lymphoma and non-Hodgkin’s lymphoma (types of cancer that affects certain cells called lymphocytes of the lymphatic system), ovarian cancer (cancer that affects the female reproductive system), breast cancer, retinoblastoma (eye cancer), etc.

Nephrotic syndrome

This medicine is used to treat a kidney disease called nephrotic syndrome in pediatric patients who have not responded adequately to steroid treatments or if the steroids produce intolerable side effects.

Benefits of cycloxan tablet

In Cancer

Cycloxan cyclophosphamide 50 mg Tablet helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. Cycloxan 50mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Nephrotic syndrome

Nephrotic syndrome is a kidney disorder that causes your body to pass too much protein in your urine accompanied with excessive swelling over various parts of the body such as around the eyes and in the feet and ankles. Cycloxan 50mg Tablet works by suppressing the immune system thereby reducing inflammation and swelling that occur in nephrotic syndrome. It reduces the protein in the urine and also helps in getting rid of the extra fluid, thereby relieving the swelling over different parts of the body. This helps to restore the normal kidney function and prevents further damage to the kidneys.

Side effects of cycloxan tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cycloxan

• Vomiting
• Nausea
• Hair loss
• Fever
• Blood in urine
• Diarrhea
• Decreased white blood cell count (neutrophils)

How to use cycloxan tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cycloxan 50mg Tablet is to be taken with food.

How cycloxan tablet works

Cycloxan cyclophosphamide tablet is an anti-cancer medication. It is an alkylating agent which works by damaging the genetic material (DNA and RNA) of the cancer cells, thereby stopping their growth and multiplication. This is how it works against cancer.

Interactions

Interaction with Alcohol

• Description
  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
• Instructions
  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Disease interactions

• Disease
  Information not available.
• Food interactions
  Information not available.
• Lab interactions
  This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

Safety advice

• Alcohol
  It is unsafe to consume alcohol with Cycloxan 50mg Tablet.
• Pregnancy
  Cycloxan 50mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
• Breast feeding
  Cycloxan 50mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
• Driving
  Cycloxan 50mg Tablet may cause side effects which could affect your ability to drive.
  Cycloxan 50mg Tablet may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive.
• Kidney
  Cycloxan 50mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Cycloxan 50mg Tablet may be needed. Please consult your doctor.
• Liver
  Cycloxan 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Cycloxan 50mg Tablet may be needed. Please consult your doctor.

Quick tips

• Cycloxan 50mg Tablet helps in the treatment of cancer.
• Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.
• Take it with food if you experience irritation of the stomach, preferably in the morning.
• Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.
• You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.
• Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.
• Do not take Tablet if you are pregnant or breastfeeding.
• Use effective contraception method to prevent pregnancy while taking this medicine.

FAQs

Q. Can Cycloxan 50mg Tablet cause infertility?

Yes, Cycloxan 50mg Tablet can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Tablet.

Q. Can Cycloxan 50mg Tablet cause cancer?

Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Cycloxan Tablet is high in the urinary bladder. Other rare cancers that may occur with use of Tablet include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.

Q. Can Cycloxan 50mg Tablet be used for non-cancer condition?

Yes, Tablet can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Cycloxan 50mg Tablet for nephrotic syndrome has not been established.

Q. Is Cycloxan 50mg Tablet chemotherapy medicine?

Yes, Tablet is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.